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Two U.S. Navy sailors were injured on Wednesday after a U.S. Navy destroyer and a supply ship collided in the Caribbean, military officials said.

"Yesterday afternoon, the Arleigh Burke-class guided missile destroyer USS Truxtun (DDG103) and the Supply-class fast combat support ship USNS Supply (T-AOE-6) collided during a replenishment-at-sea," a U.S. Southern Command spokesperson said in a statement to Fox News on Thursday. 

Two personnel reported minor injuries but are in stable condition, the official said, adding that both ships have reported sailing safely. 

The cause of the collision remains under investigation, according to the spokesperson.

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USS Truxtun sails in Arabian Sea in 2023

FILE - The USS Truxtun takes part in exercises in the Arabian Sea near Pakistan's port city of Karachi on Feb. 13, 2023. (ASIF HASSAN/AFP via Getty Images)

The Wall Street Journal first reported the at-sea collision during a ship-to-ship refueling.

Both vessels were assigned to the military buildup in the Caribbean that President Donald Trump ordered in recent months to combat drug trafficking in the region.

President Donald Trump and War Secretary Pete Hegseth

President Donald Trump stands next to Secretary of War Pete Hegseth during a ceremony for the presentation of the Mexican Border Defense Medal in the Oval Office of the White House on Dec. 15, 2025, in Washington, D.C. (Anna Moneymaker/Getty Images)

This type of replenishment operation at sea involves the transfer of supplies and fuel between two ships sailing side-by-side.

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The Journal reported that even though the Navy owns ships like the Supply, they are typically operated by civilian mariners.

USS Truxtun

The USS Truxtun pictured on an unspecified date. (Facebook/USS Truxtun )

The Truxtun had deployed earlier this month from its home port, Naval Station Norfolk in Virginia.

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This is a breaking news story; check back for updates.

Fox News' Jennifer Griffin and Liz Friden contributed to this report.